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In mathematics, the equations governing the isomonodromic deformation of meromorphic linear systems of ordinary differential equations are, in a fairly precise sense, the most fundamental exact nonlinear differential equations. As a result, their solutions and properties lie at the heart of the field of exact nonlinearity and integrable systems.
Isomonodromic deformations were first studied by Richard Fuchs, with early pioneering contributions from Lazarus Fuchs, Paul Painlevé, René Garnier, and Ludwig Schlesinger. Inspired by results in statistical mechanics, a seminal contribution to the theory was made by Michio Jimbo, Tetsuji Miwa, and Kimio Ueno, who studied cases involving irregular singularities.