Isothipendyl

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Isothipendyl

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	D04AA22 (WHO) R06AD09 (WHO)
Identifiers
IUPAC name N,N-dimethyl-1-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propan-2-amine
CAS Number	482-15-5 1225-65-6
PubChem CID	3781
DrugBank	DB08802 Y
ChemSpider	3649 Y
UNII	WVZ7K9P0JY
KEGG	D08091 Y
CompTox Dashboard (EPA)	DTXSID5048267
ECHA InfoCard	100.006.890
Chemical and physical data
Formula	C16H19N3S
Molar mass	285.41 g·mol−1
3D model (JSmol)	Interactive image
SMILES n2c1N(c3c(Sc1ccc2)cccc3)CC(N(C)C)C
InChI InChI=1S/C16H19N3S/c1-12(18(2)3)11-19-13-7-4-5-8-14(13)20-15-9-6-10-17-16(15)19/h4-10,12H,11H2,1-3H3 Y Key:OQJBSDFFQWMKBQ-UHFFFAOYSA-N Y
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Isothipendyl is a 1st generation H₁ antagonist (antihistamine) and anticholinergic used as an antipruritic.^[1] In the 2020s, at least, it is rarely used in the first line relief of allergies due to the anticholinergic side effect of somnolence but does have some limited use through topical application in the relief of insect bites and related itching (pruritus).^{[citation needed]}