Jakubov, Jakubow or Yakubov (Russian: Якубов) is a Slavic masculine surname. Its feminine counterpart is Jakubova, Jakubowa or Yakubova. It may refer to:
- Alexander Jakubov (born 1991), Czechoslovak football striker
- Apollinariya Yakubova (died 1913 or 1917), Russian revolutionary
- Ikram Yakubov, Uzbek intelligence officer
- Jakub Jakubov (born 1989), Czechoslovak football goalkeeper
- Lina Yakubova (1976–2011), Armenian documentary film producer and writer
- Maryam Yakubova (1929–1987), Uzbekistani stage and film actress
- Maryam Yakubova, Uzbekistani educator
- Mikhail Yakubov (born 1982), Russian ice hockey player
- Tom Yaacobov (born 1992), Israeli triple jumper
- Odil Yakubov (1926–2009), Uzbek writer
- Bakhrom Yakubov (1961-2021) Uzbek film director and screenwriter.