James Abercromby or Abercrombie may refer to:
- Sir James Abercrombie, 1st Baronet (c. 1680–1724), British Army officer and politician
- Sir James Abercromby, 2nd Baronet (c. 1670–1734), Scottish MP for Banffshire
- James Abercrombie (British Army officer, born 1706) (1706–1781), British general
- James Abercrombie (British Army officer, born 1732) (1732–1775), British colonel
- James Abercromby, 1st Baron Dunfermline (1776–1858), British politician
- James Abercrombie (congressman) (1792–1861), US Representative from Alabama
- James Abercrombie (inventor) (1891–1975), American inventor
- James Abercrombie (priest) (1758–1841), American Episcopal priest
- James Abercrombie Jr., American politician