James P. Allison

For other people named James Allison, see James Allison (disambiguation).

James Allison
Allison in 2018
Born
James Patrick Allison

(1948-08-07) August 7, 1948 (age 76)[4]
Alice, Texas, U.S.
EducationUniversity of Texas, Austin (BS, MS, PhD)
Known forCancer immunotherapy
Spouses
Malinda Bell
​
​
(m. 1969; div. 2012)​
​
(m. 2014)​
Children1
AwardsBreakthrough Prize in Life Sciences (2014)
Massry Prize (2014)
Tang Prize (2014)[1]
Louisa Gross Horwitz Prize (2014)
Harvey Prize (2014)
Gairdner Foundation International Award (2014)
Paul Ehrlich and Ludwig Darmstaedter Prize (2015)
Lasker-DeBakey Clinical Medical Research Award (2015)[2]
Wolf Prize (2017)
Warren Alpert Foundation Prize(2017)
Balzan Prize (2017)
Sjöberg Prize (2017)
King Faisal International Prize (2018)
Albany Medical Center Prize (2018)
Dr. Paul Janssen Award for Biomedical Research (2018)[3]
Nobel Prize in Physiology or Medicine (2018)
Scientific career
FieldsImmunology
InstitutionsM. D. Anderson Cancer Center
Weill Cornell Medicine
University of California, Berkeley
University of California, San Francisco
University of Texas at Austin
ThesisStudies on bacterial asparaginases: I. Isolation and characterization of a tumor inhibitory asparaginase from Alcaligenes ?Eutrophus. II. Insolubilization of L-Asparaginase by covalent attachment to nylon tubing (1973)
Doctoral advisorBarrie Kitto

James Patrick Allison (born August 7, 1948)[4] is an American immunologist and Nobel laureate who holds the position of professor and chair of immunology and executive director of immunotherapy platform at the MD Anderson Cancer Center in Houston, Texas.[5] Allison is Regental Professor and Founding-Director of James P. Allison Institute at the MD Anderson Cancer Center.[6]

His discoveries have led to new cancer treatments for the deadliest cancers. He is also the director of the Cancer Research Institute (CRI) scientific advisory council. He has a longstanding interest in mechanisms of T-cell development and activation, the development of novel strategies for tumor immunotherapy, and is recognized as one of the first people to isolate the T-cell antigen receptor complex protein.[7][8]

In 2014, he was awarded the Breakthrough Prize in Life Sciences; in 2018, he shared the Nobel Prize in Physiology or Medicine with Tasuku Honjo.[9][10]

  1. ^ "First Tang Prize for Biopharmaceutical Science Awarded to James P. Allison, PhD, and Tasuku Honjo, MD, PhD". www.tang-prize.org. The ASCO Post. July 10, 2014. Retrieved August 4, 2016.
  2. ^ Foundation, Lasker. "Unleashing the immune system to combat cancer | The Lasker Foundation". The Lasker Foundation. Lasker Foundation. Retrieved August 4, 2016.
  3. ^ "James Allison wins 2018 Dr. Paul Janssen Award for Biomedical Research". Retrieved September 11, 2018.
  4. ^ a b "James P. Allison – Facts – 2018". NobelPrize.org. Nobel Media AB. October 1, 2018. Retrieved October 5, 2018.
  5. ^ "James P. Allison".
  6. ^ "James P. Allison Institute".
  7. ^ "James Allison". Cancer Research Institute. Retrieved August 4, 2016.
  8. ^ Blair, Jenny (May 2, 2014). "Raising the Tail". The Alcalde. Texas Exes. Retrieved October 3, 2018.
  9. ^ "2014 Tang Prize in Biopharmaceutical Science". Archived from the original on October 20, 2017. Retrieved June 18, 2016.
  10. ^ Devlin, Hannah (October 1, 2018). "James P Allison and Tasuku Honjo win Nobel prize for medicine". the Guardian. Retrieved October 1, 2018.