James Pepper may refer to:
- Jim Pepper (1941–1992), Kaw Nation and American jazz saxophonist, composer, and singer
- James Auburn Pepper (1915–1985), farmer and political figure in Saskatchewan
- James Pepper, cowboy involved in New Mexico's Lincoln County War as an ally of John Chisum
- James E. Pepper, American whiskey brand
This disambiguation page lists articles associated with the title James Pepper.
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