James Preston

James Preston may refer to:

• James H. Preston (1860–1938), mayor of Baltimore
• James Moore Preston (1873–1962), American painter and illustrator
• James Patton Preston (1774–1843), U.S. political figure
• James Preston (cricketer) (1792–1842), English cricketer
• James B. Preston (politician) (died 1902), American politician
• James B. Preston (1926–2004), American neurophysiologist
• James Preston (runner), track and field athlete from New Zealand