James Sharpe

James Sharpe may refer to:

• James Sharpe (Australian politician) (1868–1935)
• James Sharpe (Canadian politician) (1846–1935), English-born pioneer and politician in Ontario
• James Sharpe (Dutch politician) (born 1962), businessman and athlete
• James Sharpe (Jesuit) (1577–1630), English professor of scripture
• James Sharpe (historian) (1946–2024), English social historian, University of York