James Wise

James Wise may refer to:

• James Wise (civil surgeon) (died 1886), British civil surgeon in Dhaka, British India
• James E. Wise Jr., U.S. Navy officer
• James H. Wise (bishop) (died 1939), bishop of Kansas in the Episcopal Church
• James H. Wise (politician) (1912–1976), American politician
• James W. Wise (1868–1925), U.S. Representative from Georgia