Janice McKenzie Cole is an American attorney who served as the United States Attorney for the Eastern District of North Carolina (1994–2001) under President Bill Clinton.
During her tenure as U.S. Attorney, she helped introduce five communities to the United States Department of Justice's Weed and Seed crime-prevention program. Cole has been honored as Woman of the Year by the East Carolina University Branch of the American Association of University Women and Tarheel of the Week by The News and Observer.