 Japanese encephalitis vaccine Encevac | |
| Vaccine description | |
|---|---|
| Target | Japanese encephalitis |
| Vaccine type | Inactivated or attenuated |
| Clinical data | |
| Trade names | Ixiaro, Imojev |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a607019 |
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Japanese encephalitis vaccine is a vaccine that protects against Japanese encephalitis.[2] The vaccines are more than 90% effective.[2] The duration of protection with the vaccine is not clear but its effectiveness appears to decrease over time.[2] Doses are given either by injection into a muscle or just under the skin.[2]
It is recommended as part of routine immunizations in countries where the disease is a problem.[2] One or two doses are given depending on the version of the vaccine.[2] Extra doses are not typically needed in areas where the disease is common.[2] In those with HIV/AIDS or those who are pregnant an inactivated vaccine should be used.[2] Immunization of travellers who plan to spend time outdoors in areas where the disease is common is recommended.[2]
The vaccines are relatively safe.[2] Pain and redness may occur at the site of injection.[2] As of 2015[update], 15 different vaccines are available:[2] some are based on recombinant DNA techniques, others weakened virus, and others inactivated virus.[2]
The Japanese encephalitis vaccines first became available in the 1930s.[3] It is on the World Health Organization's List of Essential Medicines.[4][5]
- ^ a b Use During Pregnancy and Breastfeeding
- ^ a b c d e f g h i j k l m "Japanese Encephalitis Vaccines: WHO position paper – February 2015". Relevé Épidémiologique Hebdomadaire. 90 (9): 69–87. February 2015. hdl:10665/242325. PMID 25726573.
"Summary of the WHO Position Paper on Vaccines against Japanese encephalitis (JE)" (PDF). Archived from the original (PDF) on 6 June 2015. - ^ Paulke-Korinek M, Kollaritsch H (2008). "Japanese encephalitis and vaccines: past and future prospects". Wiener Klinische Wochenschrift. 120 (19-20 Suppl 4): 15–19. doi:10.1007/s00508-008-1071-9. PMID 19066766. S2CID 7170010.
Furthermore, vaccines against JEV have been available since the 1930s.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.