Jason McLellan

Jason McLellan
NationalityAmerican
Education
Scientific career
FieldsStructural Biology
InstitutionsUniversity of Texas at Austin
Websitewww.mclellanlab.org

Jason S. McLellan is a structural biologist, professor in the Department of Molecular Biosciences and Robert A. Welch Chair in Chemistry at The University of Texas at Austin[1] who specializes in understanding the structure and function of viral proteins, including those of coronaviruses.[2] His research focuses on applying structural information to the rational design of vaccines and other therapies for viruses,[3] including SARS-CoV-2, the novel coronavirus that causes COVID-19,[4] and respiratory syncytial virus (RSV).[5] McLellan and his team collaborated with researchers at the National Institute of Allergy and Infectious Diseases’ Vaccine Research Center to design a stabilized version of the SARS-CoV-2 spike protein,[6][7][8][9] which biotechnology company Moderna used as the basis for the vaccine mRNA-1273,[10][11][12][13] the first COVID-19 vaccine candidate to enter phase I clinical trials in the U.S.[14] At least three other vaccines use this modified spike protein: those from Pfizer and BioNTech; Johnson & Johnson and Janssen Pharmaceuticals; and Novavax.[7][15]

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