Jeffrey Harold Siewerdsen (born 1969) is an Americanphysicist and biomedical engineer who is a Professor of Imaging Physics at The University of Texas MD Anderson Cancer Center as well as Biomedical Engineering, Computer Science, Radiology, and Neurosurgery at Johns Hopkins University.He is among the original inventors of cone-beam CT-guided radiotherapy[1] as well as weight-bearing cone-beam CT[2][3] for musculoskeletal radiology and orthopedic surgery. His work also includes the early development of flat-panel detectors on mobile C-arms for intraoperative cone-beam CT in image-guided surgery.[4] He developed early models for the signal and noise performance of flat-panel detectors[5] and later extended such analysis to dual-energy imaging[6] and 3D imaging performance in cone-beam CT.[7] He founded the ISTAR Lab (Imaging for Surgery, Therapy, and Radiology) in the Department of Biomedical Engineering, the Carnegie Center for Surgical Innovation at Johns Hopkins Hospital, and the Surgical Data Science Program at the Institute for Data Science in Oncology at The University of Texas MD Anderson Cancer Center.
^Jaffray, David A; Siewerdsen, Jeffrey H; Wong, John W; Martinez, Alvaro A (2002). "Flat-panel cone-beam computed tomography for image-guided radiation therapy". International Journal of Radiation Oncology, Biology, Physics. 53 (5): 1337–1349. doi:10.1016/s0360-3016(02)02884-5. PMID12128137.
^Siewerdsen, J. H.; Moseley, D. J.; Burch, S.; Bisland, S. K.; Bogaards, A.; Wilson, B. C.; Jaffray, D. A. (2005-01-01). "Volume CT with a flat-panel detector on a mobile, isocentric C-arm: Pre-clinical investigation in guidance of minimally invasive surgery". Medical Physics. 32 (1): 241–254. Bibcode:2005MedPh..32..241S. doi:10.1118/1.1836331. ISSN2473-4209. PMID15719975.