Joseph Iacone (born 1940) is a former American football running back. He played college football at West Chester State University from 1960 to 1962 where he was twice named a Little All-America and All-East fullback. He was the leading rusher in NCAA Division II as a sophomore and set career and single-season Pennsylvania State Athletic Conference rushing and scoring records that remained unbroken for two to three decades. He averaged 139.5 yards per game over his three years at West Chester, which ranked second all-time in NCAA Division II history at the time.