John Dwyer may refer to:
- John Dwyer (Australian judge) (1879–1966), Australian judge
- John Dwyer (baseball) (active 1882), American baseball player
- John Dwyer (field hockey) (born 1928), Australian Olympic hockey player
- John Dwyer (medicine) (born 1939), Australian professor of medicine
- John Dwyer (musician) (born 1974), American musician
- John Dwyer (police officer) (active 2012–2016), British police officer
- John Dwyer (VC) (1890–1962), Australian soldier
- John M. Dwyer (born 1926), American set decorator
- John J. Dwyer (1856–1911), American architect
- Jack Dwyer (1927–1997), American football player