John Edgar Dick

John Dick
FRS FRSC
John Dick at the Royal Society admissions day in London in 2014
Born
John Edgar Dick

1954 (age 69–70)
Alma materUniversity of Manitoba (PhD)
AwardsRobert L. Noble Prize (2000)
Scientific career
Fields
Institutions
Thesis[ProQuest 303339990 Studies on Ribonucleotide Reductase from Normal Senescing Human Diploid Fibroblasts] (1984)
Websitejdstemcellresearch.ca

John Edgar Dick FRS FRSC[2] (born 1954) is Canada Research Chair in Stem Cell Biology, Senior Scientist at the Princess Margaret Cancer Centre, University Health Network and Professor in the Department of Molecular Genetics at the University of Toronto in Canada.[3] Dick is credited with first identifying cancer stem cells in certain types of human leukemia.[4] His revolutionary findings highlighted the importance of understanding that not all cancer cells are the same and thus spawned a new direction in cancer research.[1][5][6][7] Dick is also known for his demonstration of a blood stem cell's ability to replenish the blood system of a mouse, his development of a technique to enable an immune-deficient mouse to carry and produce human blood, and his creation of the world's first mouse with human leukemia. [5][8][9][10][3][11][12]

  1. ^ a b Baker, M. (2009). "John Dick: Careful assays for cancer stem cells". Nature Reports Stem Cells: 1. doi:10.1038/stemcells.2009.47.
  2. ^ Anon (2014). "Dr John Dick FRS". royalsociety.org. London: Royal Society. One or more of the preceding sentences incorporates text from the royalsociety.org website where:

    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --"Terms, conditions and policies | Royal Society". Archived from the original on 2016-11-11. Retrieved 2018-09-12.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  3. ^ a b John Edgar Dick publications indexed by the Scopus bibliographic database. (subscription required)
  4. ^ Dick, J (2013). "Q&A: John Dick on Stem Cells and Cancer". Cancer Discovery. 3 (2): 131. doi:10.1158/2159-8290.CD-ND2013-002. PMID 23400460.
  5. ^ a b Meet the A-Team of stem-cell science. Retrieved from The Globe and Mail on November 27, 2006. Archived February 20, 2007, at the Wayback Machine
  6. ^ Canadian Cancer Society- John Dick Bio Archived May 3, 2007, at the Wayback Machine
  7. ^ University Health Network- John E Dick Bio
  8. ^ Canadian researchers 'create' leukemia stem cell, watch disease unfold. CBC News, April 26, 2007.[dead link]
  9. ^ Bonnet, D.; Dick, J. E. (1997). "Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell". Nature Medicine. 3 (7): 730–7. doi:10.1038/nm0797-730. PMID 9212098. S2CID 205381050.
  10. ^ o’Brien, C. A.; Pollett, A.; Gallinger, S.; Dick, J. E. (2006). "A human colon cancer cell capable of initiating tumour growth in immunodeficient mice". Nature. 445 (7123): 106–10. doi:10.1038/nature05372. PMID 17122772. S2CID 4419499.
  11. ^ Larochelle, A.; Vormoor, J.; Hanenberg, H.; Wang, J. C. Y.; Bhatia, M.; Lapidot, T.; Moritz, T.; Murdoch, B.; Xiao, X. L.; Kato, I.; Williams, D. A.; Dick, J. E. (1996). "Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy". Nature Medicine. 2 (12): 1329–37. doi:10.1038/nm1296-1329. PMID 8946831. S2CID 2975811.
  12. ^ Clarke, M. F.; Dick, J. E.; Dirks, P. B.; Eaves, C. J.; Jamieson, C. H. M.; Jones, D. L.; Visvader, J.; Weissman, I. L.; Wahl, G. M. (2006). "Cancer Stem Cells--Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells". Cancer Research. 66 (19): 9339–44. doi:10.1158/0008-5472.CAN-06-3126. PMID 16990346.