John Erskine, 1st Earl of Mar (died 28 October 1572) was a Scottish aristocrat and politician. He was the custodian of the infant James VI of Scotland and Regent of Scotland.
Erskine was a son of John Erskine, 5th Lord Erskine and Lady Margaret Campbell, a daughter of Archibald Campbell, 2nd Earl of Argyll. His father was a guardian of King James V and afterwards of Mary, Queen of Scots.