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John Isaac Guion | |
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| 17th Governor of Mississippi | |
| In office February 3, 1851 – November 4, 1851 | |
| Preceded by | John A. Quitman |
| Succeeded by | James Whitfield |
| Member of the Mississippi State Senate | |
| In office 1842–1851 | |
| Personal details | |
| Born | November 18, 1802 Adams County, Mississippi Territory, U.S. |
| Died | June 6, 1855 (aged 52) Jackson, Mississippi, U.S. |
John Isaac Guion (November 18, 1802 – June 6, 1855) was an American politician from Mississippi who served as Governor in 1851.
