John Major (born 1943) was Prime Minister of the United Kingdom from 1990 to 1997.
John Major or Sir John Major may also refer to:
- John Major (philosopher) (1467–1550, also called John Mair), Scottish philosopher and historian
- John Major (17th-century English MP) (died 1628), English politician and Member of Parliament
- Sir John Major, 1st Baronet (1698–1781), English merchant and Member of Parliament
- John Major (publisher) (1782–1849), English publisher and bookseller
- John Richardson Major (1797–1876), English clergyman and schoolmaster
- John Major (cricketer) (1861–1930), English cricketer
- John Kenneth Major (1928–2009), best known as Ken Major, English architect, author and world authority on industrial archaeology
- John C. Major (born 1931), former Justice of the Supreme Court of Canada
- John Major (rugby union) (born 1940), New Zealand rugby union player
- John Major Jenkins (born 1964), American author and populariser of the Maya calendar
- John Major: The Autobiography, a 1999 political memoir by the prime minister