John Sampen (born 1949) is an American classical saxophonist.
Sampen's degrees are from Northwestern University (B.M., 1971; M.M., 1972; and Doctor of Music, 1984). His teachers included Frederick Hemke, Larry Teal, and Donald Sinta. He has served as professor of saxophone at Bowling Green State University in Bowling Green, Ohio since 1977. His wife is the composer and pianist Marilyn Shrude.
Sampen plays all types of the saxophone. He specializes in new music, and has commissioned over 60 new works for these instruments, from composers such as Samuel Adler, William Albright, Milton Babbitt, William Bolcom, John Cage, Michael Colgrass, John Harbison, Donald Martino, Ryo Noda, Pauline Oliveros, Bernard Rands, Gunther Schuller, Elliott Schwartz, Marilyn Shrude, Morton Subotnick, and Vladimir Ussachevsky.