John Sulston

Sir
John Sulston
CH FRS MAE
Sulston in 2008
Born
John Edward Sulston

(1942-03-27)27 March 1942[6]
Fulmer, Buckinghamshire, England
Died6 March 2018(2018-03-06) (aged 75)
EducationMerchant Taylors' School, Northwood
Alma materUniversity of Cambridge (BA, PhD)
Known forGenome sequencing of Caenorhabditis elegans and humans[7][8][9][10]
Sulston score[11]
Apoptosis
Spouse
Daphne Edith Bate
​
(m. 1966)​
[6]
Children1 son, 1 daughter[6]
Awards
Scientific career
Fields
Institutions
ThesisAspects of oligoribonucleotide synthesis (1966)
Doctoral advisorColin Reese[4][5]
Websitesanger.ac.uk/people/faculty/honorary-faculty/john-sulston

Sir John Edward Sulston CH FRS MAE (27 March 1942 – 6 March 2018[12][13]) was a British biologist and academic who won the Nobel Prize in Physiology or Medicine for his work on the cell lineage and genome of the worm Caenorhabditis elegans in 2002 with his colleagues Sydney Brenner and Robert Horvitz at the MRC Laboratory of Molecular Biology.[14] He was a leader in human genome research and Chair of the Institute for Science, Ethics and Innovation at the University of Manchester.[15][16][17] Sulston was in favour of science in the public interest, such as free public access of scientific information and against the patenting of genes and the privatisation of genetic technologies.[18]

  1. ^ Cite error: The named reference membo was invoked but never defined (see the help page).
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  6. ^ a b c Anon (2015). "Sulston, Sir John (Edward)". Who's Who (online Oxford University Press ed.). A & C Black. doi:10.1093/ww/9780199540884.013.36669. (Subscription or UK public library membership required.)
  7. ^ Wilson, R.; Ainscough, R.; Anderson, K.; Baynes, C.; Berks, M.; Bonfield, J.; Burton, J.; Connell, M.; Copsey, T.; Cooper, J.; Coulson, A.; Craxton, M.; Dear, S.; Du, Z.; Durbin, R.; Favello, A.; Fraser, A.; Fulton, L.; Gardner, A.; Green, P.; Hawkins, T.; Hillier, L.; Jier, M.; Johnston, L.; Jones, M.; Kershaw, J.; Kirsten, J.; Laisster, N.; Latreille, P.; Lightning, J. (1994). "2.2 Mb of contiguous nucleotide sequence from chromosome III of C. Elegans". Nature. 368 (6466): 32–38. Bibcode:1994Natur.368...32W. doi:10.1038/368032a0. PMID 7906398. S2CID 21450455.
  8. ^ Sulston, J.; Brenner, S. (1974). "The DNA of Caenorhabditis elegans". Genetics. 77 (1): 95–104. doi:10.1093/genetics/77.1.95. PMC 1213121. PMID 4858229.
  9. ^ Sulston, J. E.; Schierenberg, E.; White, J. G.; Thomson, J. N. (1983). "The embryonic cell lineage of the nematode Caenorhabditis elegans". Developmental Biology. 100 (1): 64–119. doi:10.1016/0012-1606(83)90201-4. PMID 6684600.
  10. ^ Sulston, J. E.; Horvitz, H. R. (1977). "Post-embryonic cell lineages of the nematode, Caenorhabditis elegans". Developmental Biology. 56 (1): 110–156. doi:10.1016/0012-1606(77)90158-0. PMID 838129.
  11. ^ Sulston, J.; Mallett, F.; Staden, R.; Durbin, R.; Horsnell, T.; Coulson, A. (1988). "Software for genome mapping by fingerprinting techniques". Computer Applications in the Biosciences. 4 (1): 125–132. doi:10.1093/bioinformatics/4.1.125. PMID 2838135.
  12. ^ Kolata, Gina (15 March 2018). "John E. Sulston, 75, Dies; Found Clues to Genes in a Worm". The New York Times.
  13. ^ Waterston, Robert H.; Ferry, Georgina (2019). "Sir John Edward Sulston CH. 27 March 1942 – 6 March 2018". Biographical Memoirs of Fellows of the Royal Society. 67: 421–447. doi:10.1098/rsbm.2019.0014. S2CID 186212646.
  14. ^ Ferry, Georgina (11 March 2018). "Sir John Sulston obituary". The Guardian. ISSN 0261-3077. Retrieved 14 July 2023.
  15. ^ "Professor Sir John Sulston - personal details". The University of Manchester. Archived from the original on 11 October 2009. Retrieved 6 November 2014.
  16. ^ Gitschier, Jane (2006). "Knight in Common Armor: An Interview with Sir John Sulston". PLOS Genetics. 2 (12): e225. doi:10.1371/journal.pgen.0020225. PMC 1756915. PMID 17196043. Open access icon
  17. ^ Sulston, J. (2002). "A conversation with John Sulston". The Yale Journal of Biology and Medicine. 75 (5–6): 299–306. PMC 2588810. PMID 14580111.
  18. ^ Ivan Oransky, Adam Marcus John Sulston. obituary 7 April 2018, The Lancet