Jpx (gene)

JPX
Identifiers
Aliases	JPX, DCBALD06, ENOX, LINC00183, NCRNA00183, Jpx, JPX transcript, XIST activator (non-protein coding), JPX transcript, XIST activator
External IDs	OMIM: 300832; GeneCards: JPX; OMA:JPX - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	74,070,408 bp
RNA expression pattern
	Top expressed in
	epithelium of colon; ; Achilles tendon; ; right uterine tube; ; bone marrow cells; ; anterior pituitary; ; internal globus pallidus; ; C1 segment; ; left ovary; ; corpus callosum; ; right ovary;
	n/a
	More reference expression data
	n/a
Orthologs
	554203
	n/a
	ENSG00000225470
	n/a
	n; a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

In molecular biology, JPX transcript, XIST activator (non-protein coding), also known as Jpx, is a long non-coding RNA. In humans, it is located on the X chromosome. It was identified during sequence analysis of the X inactivation centre, surrounding the Xist gene.^[3] Jpx upregulates expression of Xist.^[4]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000225470 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chureau C, Prissette M, Bourdet A, Barbe V, Cattolico L, Jones L, et al. (2002). "Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine". Genome Res. 12 (6): 894–908. doi:10.1101/gr.152902. PMC 1383731. PMID 12045143.
^ Tian D, Sun S, Lee JT (2010). "The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation". Cell. 143 (3): 390–403. doi:10.1016/j.cell.2010.09.049. PMC 2994261. PMID 21029862.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000225470 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12045143-3] Chureau C, Prissette M, Bourdet A, Barbe V, Cattolico L, Jones L, et al. (2002). "Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine". Genome Res. 12 (6): 894–908. doi:10.1101/gr.152902. PMC 1383731. PMID 12045143.

[pmid21029862-4] Tian D, Sun S, Lee JT (2010). "The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation". Cell. 143 (3): 390–403. doi:10.1016/j.cell.2010.09.049. PMC 2994261. PMID 21029862.

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