The Juan Bautista de Anza National Historic Trail is a 1,210-mile (1,950 km) trail extending from Nogales on the U.S.-Mexico border in Arizona, through the California desert and coastal areas in Southern California and the Central Coast region to San Francisco.[1] The trail commemorates the 1775–1776 land route that Spanish commander Juan Bautista de Anza took from the Sonora y Sinaloa Province of New Spain in Colonial Mexico through to Las Californias Province. The goal of the trip was to establish a mission and presidio on the San Francisco Bay. The trail was an attempt to ease the course of Spanish colonization of California by establishing a major land route north for many to follow. It was used for about five years before being closed by the Quechan (Yuma) Indians in 1781 and kept closed for the next 40 years.[1] It is a National Historic Trail administered by the National Park Service and was also designated a National Millennium Trail.