JunD

JUND
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3U86
Identifiers
Aliases	JUND, AP-1, JunD, JunD proto-oncogene, AP-1 transcription factor subunit
External IDs	OMIM: 165162; MGI: 96648; HomoloGene: 3910; GeneCards: JUND; OMA:JUND - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	18,281,622 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	71,153,265 bp
RNA expression pattern
	Top expressed in
	cardia; ; vena cava; ; nipple; ; paraflocculus of cerebellum; ; pylorus; ; renal medulla; ; lactiferous duct; ; trachea; ; saphenous vein; ; Brodmann area 10;
	Top expressed in
	granulocyte; ; adrenal gland; ; bone marrow; ; islet of Langerhans; ; ileum; ; ganglionic eminence; ; cerebellar cortex; ; primary visual cortex; ; striatum of neuraxis; ; urinary bladder;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; transcription coactivator activity; protein binding; enzyme binding; double-stranded DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; transcription factor binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; nuclear receptor binding;
Cellular component	protein-DNA complex; chromatin; nucleus; transcription factor AP-1 complex; protein-containing complex; nucleoplasm; transcription regulator complex;
Biological process	cellular response to calcium ion; response to cytokine; regulation of transcription, DNA-templated; response to organic cyclic compound; response to light stimulus; regulation of cell death; human ageing; response to peptide hormone; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; transcription, DNA-templated; regulation of cell cycle; cellular response to hormone stimulus; positive regulation of osteoblast differentiation; regulation of cell population proliferation; circadian rhythm; positive regulation of cell differentiation; osteoblast development; response to radiation; response to cAMP; response to lipopolysaccharide; response to mechanical stimulus; regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; response to organic substance;
	Sources:Amigo / QuickGO
Orthologs
	3727
	16478
	ENSG00000130522
	ENSMUSG00000071076
	P17535
	P15066
	NM_005354; NM_001286968
	NM_001286944; NM_010592
	NP_001273897; NP_005345
	NP_001273873; NP_034722
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor JunD is a protein that in humans is encoded by the JUND gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000130522 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000071076 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nomura N, Ide M, Sasamoto S, Matsui M, Date T, Ishizaki R (July 1990). "Isolation of human cDNA clones of jun-related genes, jun-B and jun-D". Nucleic Acids Res. 18 (10): 3047–8. doi:10.1093/nar/18.10.3047. PMC 330838. PMID 2112242.
^ Berger I, Shaul Y (June 1991). "Structure and function of human jun-D". Oncogene. 6 (4): 561–6. PMID 1903194.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000130522 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000071076 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2112242-5] Nomura N, Ide M, Sasamoto S, Matsui M, Date T, Ishizaki R (July 1990). "Isolation of human cDNA clones of jun-related genes, jun-B and jun-D". Nucleic Acids Res. 18 (10): 3047–8. doi:10.1093/nar/18.10.3047. PMC 330838. PMID 2112242.

[pmid1903194-6] Berger I, Shaul Y (June 1991). "Structure and function of human jun-D". Oncogene. 6 (4): 561–6. PMID 1903194.

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