Junying Yuan

Junying Yuan
Born (1958-10-03) October 3, 1958 (age 66)
Shanghai, China
NationalityAmerican
Alma materFudan University
Harvard University
Massachusetts Institute of Technology
Known forApoptosis research
Necroptosis
Scientific career
FieldsBiology
Cell death
InstitutionsHarvard Medical School
Doctoral advisorH. Robert Horvitz

Junying Yuan (Chinese: 袁钧瑛; pinyin: Yuán Jūnyīng, born October 3, 1958) is the Elizabeth D. Hay Professor of Cell Biology at Harvard Medical School,[1] best known for her work in cell death. Early in her career, she contributed significant findings to the discovery and characterization of apoptosis.[2][3] More recently, she was responsible for the discovery of the programmed form of necrotic cell death known as necroptosis.[4]

  1. ^ "Yuan Named Hay Professor of Cell Biology". HMS News. Retrieved 13 May 2015.
  2. ^ Yuan, J. Y.; Horvitz, H. R. (1990). "The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death". Developmental Biology. 138 (1): 33–41. doi:10.1016/0012-1606(90)90174-h. PMID 2307287.
  3. ^ Yuan, J; Horvitz, H. R. (1992). "The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death". Development. 116 (2): 309–20. doi:10.1242/dev.116.2.309. PMID 1286611.
  4. ^ Degterev, A; Huang, Z; Boyce, M; Li, Y; Jagtap, P; Mizushima, N; Cuny, G. D.; Mitchison, T. J.; Moskowitz, M. A.; Yuan, J (2005). "Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury". Nature Chemical Biology. 1 (2): 112–9. doi:10.1038/nchembio711. PMID 16408008. S2CID 866321.