KCNAB2

KCNAB2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1ZSX
Identifiers
Aliases	KCNAB2, AKR6A5, HKvbeta2, HKvbeta2.1, HKvbeta2.2, KCNA2B, KV-BETA-2, potassium voltage-gated channel subfamily A regulatory beta subunit 2
External IDs	OMIM: 601142; MGI: 109239; HomoloGene: 56492; GeneCards: KCNAB2; OMA:KCNAB2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	6,101,193 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	152,562,367 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; right frontal lobe; ; pons; ; cingulate gyrus; ; anterior cingulate cortex; ; granulocyte; ; Brodmann area 9; ; nucleus accumbens; ; amygdala; ; spinal ganglia;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; neural layer of retina; ; superior frontal gyrus; ; hippocampus proper; ; primary visual cortex; ; primary motor cortex; ; pontine nuclei; ; lateral geniculate nucleus; ; anterior horn of spinal cord; ; medial geniculate nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	aldo-keto reductase (NADP) activity; voltage-gated ion channel activity; potassium channel regulator activity; voltage-gated potassium channel activity; oxidoreductase activity;
Cellular component	axon terminus; cytoplasm; integral component of membrane; cytosol; cell projection; membrane; postsynaptic density; extrinsic component of cytoplasmic side of plasma membrane; voltage-gated potassium channel complex; plasma membrane; synapse; axon; cell junction; pinceau fiber; neuron projection; microtubule; cytoskeleton; juxtaparanode region of axon; specific granule membrane; tertiary granule membrane;
Biological process	NADPH oxidation; regulation of protein localization to cell surface; regulation of ion transmembrane transport; ion transport; potassium ion transport; neuromuscular process; hematopoietic progenitor cell differentiation; potassium ion transmembrane transport; regulation of potassium ion transmembrane transport; neutrophil degranulation; ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	8514
	16498
	ENSG00000069424
	ENSMUSG00000028931
	Q13303
	P62482
NM_001199860; NM_001199861; NM_001199862; NM_001199863; NM_003636;
	NM_172130
NM_001252654; NM_001252655; NM_001252656; NM_010598; NM_001355172;
	NM_001355173
NP_001186789; NP_001186790; NP_001186791; NP_001186792; NP_003627;
	NP_742128; NP_001186789.1; NP_001186790.1; NP_003627.1
NP_001239583; NP_001239584; NP_001239585; NP_034728; NP_001342101;
	NP_001342102
	Wikidata
View/Edit Human	View/Edit Mouse

Voltage-gated potassium channel subunit beta-2 is a protein that in humans is encoded by the KCNAB2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000069424 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028931 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Schultz D, Litt M, Smith L, Thayer M, McCormack K (Mar 1997). "Localization of two potassium channel beta subunit genes, KCNA1B and KCNA2B". Genomics. 31 (3): 389–91. doi:10.1006/geno.1996.0065. PMID 8838324.
^ "Entrez Gene: KCNAB2 potassium voltage-gated channel, shaker-related subfamily, beta member 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000069424 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028931 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8838324-5] Schultz D, Litt M, Smith L, Thayer M, McCormack K (Mar 1997). "Localization of two potassium channel beta subunit genes, KCNA1B and KCNA2B". Genomics. 31 (3): 389–91. doi:10.1006/geno.1996.0065. PMID 8838324.

[entrez-6] "Entrez Gene: KCNAB2 potassium voltage-gated channel, shaker-related subfamily, beta member 2".

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