KCNG3

KCNG3
Identifiers
Aliases	KCNG3, KV10.1, KV6.3, potassium voltage-gated channel modifier subfamily G member 3
External IDs	OMIM: 606767; MGI: 2663923; HomoloGene: 15168; GeneCards: KCNG3; OMA:KCNG3 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	42,493,982 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	83,939,324 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; prefrontal cortex; ; right adrenal gland; ; left adrenal gland; ; right adrenal cortex; ; middle temporal gyrus; ; endometrium; ; left adrenal cortex; ; Brodmann area 23; ; entorhinal cortex;
	Top expressed in
	secondary oocyte; ; zygote; ; primary oocyte; ; epiblast; ; dentate gyrus of hippocampal formation granule cell; ; embryo; ; adrenal gland; ; hippocampus proper; ; ovary; ; Cortex of frontal lobe;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity; ion channel activity; potassium channel activity; protein binding; delayed rectifier potassium channel activity; voltage-gated ion channel activity;
Cellular component	cytoplasm; integral component of membrane; voltage-gated potassium channel complex; plasma membrane; endoplasmic reticulum; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; protein homooligomerization; ion transport; transmembrane transport; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	170850
	225030
	ENSG00000171126
	ENSMUSG00000045053
	Q8TAE7
	P59053
	NM_172344; NM_133329
	NM_153512
	NP_579875; NP_758847
	NP_705732
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily G member 3 is a protein that in humans is encoded by the KCNG3 gene.^[5]^[6] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171126 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000045053 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sano Y, Mochizuki S, Miyake A, Kitada C, Inamura K, Yokoi H, Nozawa K, Matsushime H, Furuichi K (Feb 2002). "Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K(+) channel Kv2.1". FEBS Lett. 512 (1–3): 230–4. doi:10.1016/S0014-5793(02)02267-6. PMID 11852086. S2CID 83987133.
^ ^a ^b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000171126 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000045053 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11852086-5] Sano Y, Mochizuki S, Miyake A, Kitada C, Inamura K, Yokoi H, Nozawa K, Matsushime H, Furuichi K (Feb 2002). "Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K(+) channel Kv2.1". FEBS Lett. 512 (1–3): 230–4. doi:10.1016/S0014-5793(02)02267-6. PMID 11852086. S2CID 83987133.

[pmid16382104-6] Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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