KCNG4

KCNG4
Identifiers
Aliases	KCNG4, KV6.3, KV6.4, potassium voltage-gated channel modifier subfamily G member 4
External IDs	OMIM: 607603; MGI: 1913983; HomoloGene: 23553; GeneCards: KCNG4; OMA:KCNG4 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	84,240,012 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	120,362,419 bp
RNA expression pattern
	Top expressed in
	testicle; ; amygdala; ; substantia nigra; ; hypothalamus; ; C1 segment; ; prefrontal cortex; ; hippocampus proper; ; putamen; ; anterior cingulate cortex; ; nucleus accumbens;
	Top expressed in
	facial motor nucleus; ; cerebellar cortex; ; knee joint; ; lumbar subsegment of spinal cord; ; vastus lateralis muscle; ; habenula; ; triceps brachii muscle; ; temporal muscle; ; cerebellar vermis; ; deep cerebellar nuclei;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity; ion channel activity; potassium channel activity; delayed rectifier potassium channel activity; transmembrane transporter binding; voltage-gated ion channel activity;
Cellular component	integral component of membrane; voltage-gated potassium channel complex; plasma membrane; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; protein homooligomerization; ion transport; transmembrane transport; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	93107
	66733
	ENSG00000168418
	ENSMUSG00000045246
	Q8TDN1
	Q80XM3
	NM_172347; NM_133490
	NM_025734; NM_001357210
	NP_758857
	NP_080010; NP_001344139
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily G member 4 is a protein that in humans is encoded by the KCNG4 gene.^[5]^[6] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168418 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000045246 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (Jun 2002). "Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome". Proc Natl Acad Sci U S A. 99 (12): 7986–91. Bibcode:2002PNAS...99.7986O. doi:10.1073/pnas.122617999. PMC 123007. PMID 12060745.
^ ^a ^b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000168418 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000045246 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12060745-5] Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (Jun 2002). "Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome". Proc Natl Acad Sci U S A. 99 (12): 7986–91. Bibcode:2002PNAS...99.7986O. doi:10.1073/pnas.122617999. PMC 123007. PMID 12060745.

[pmid16382104-6] Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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