KCNIP2

KCNIP2
Identifiers
Aliases	KCNIP2, KCHIP2, potassium voltage-gated channel interacting protein 2
External IDs	OMIM: 604661; MGI: 2135916; HomoloGene: 23710; GeneCards: KCNIP2; OMA:KCNIP2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	101,843,920 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	45,804,500 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; right auricle; ; nucleus accumbens; ; caudate nucleus; ; putamen; ; right frontal lobe; ; left ventricle; ; anterior cingulate cortex; ; cardiac muscle tissue of right atrium; ; right hemisphere of cerebellum;
	Top expressed in
	interventricular septum; ; olfactory tubercle; ; dentate gyrus; ; lateral septal nucleus; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; nucleus accumbens; ; primary visual cortex; ; anterior amygdaloid area; ; myocardium of ventricle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; potassium channel activity; ER retention sequence binding; transmembrane transporter binding; protein N-terminus binding; metal ion binding; voltage-gated ion channel activity; protein binding; A-type (transient outward) potassium channel activity; identical protein binding; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization; potassium channel regulator activity;
Cellular component	cytoplasm; membrane; plasma membrane; potassium channel complex; voltage-gated potassium channel complex;
Biological process	clustering of voltage-gated potassium channels; muscle contraction; regulation of heart contraction; regulation of ion transmembrane transport; ion transport; detection of calcium ion; potassium ion transport; membrane repolarization; regulation of cation channel activity; potassium ion transmembrane transport; regulation of potassium ion transmembrane transport; signal transduction; chemical synaptic transmission; membrane repolarization during cardiac muscle cell action potential; potassium ion export across plasma membrane; positive regulation of potassium ion export across plasma membrane; positive regulation of voltage-gated potassium channel activity; cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	30819
	80906
	ENSG00000120049
	ENSMUSG00000025221
	Q9NS61
	Q9JJ69
NM_014591; NM_173191; NM_173192; NM_173193; NM_173194;
	NM_173195; NM_173197; NM_173342
	NM_001276358; NM_030716; NM_145703; NM_145704
NP_055406; NP_775283; NP_775284; NP_775285; NP_775286;
	NP_775287; NP_775289
	NP_001263287; NP_109641; NP_663749; NP_663750
	Wikidata
View/Edit Human	View/Edit Mouse

K_v channel-interacting protein 2 also known as KChIP2 is a protein that in humans is encoded by the KCNIP2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120049 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025221 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ An WF, Bowlby MR, Betty M, Cao J, Ling HP, Mendoza G, Hinson JW, Mattsson KI, Strassle BW, Trimmer JS, Rhodes KJ (Feb 2000). "Modulation of A-type potassium channels by a family of calcium sensors". Nature. 403 (6769): 553–6. Bibcode:2000Natur.403..553A. doi:10.1038/35000592. PMID 10676964. S2CID 4419472.
^ "Entrez Gene: KCNIP2 Kv channel interacting protein 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000120049 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025221 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10676964-5] An WF, Bowlby MR, Betty M, Cao J, Ling HP, Mendoza G, Hinson JW, Mattsson KI, Strassle BW, Trimmer JS, Rhodes KJ (Feb 2000). "Modulation of A-type potassium channels by a family of calcium sensors". Nature. 403 (6769): 553–6. Bibcode:2000Natur.403..553A. doi:10.1038/35000592. PMID 10676964. S2CID 4419472.

[entrez-6] "Entrez Gene: KCNIP2 Kv channel interacting protein 2".

[1]

[2]

[3]

[4]

[5]

[6]