KCNK17

KCNK17
Identifiers
Aliases	KCNK17, K2p17.1, TALK-2, TALK2, TASK-4, TASK4, potassium two pore domain channel subfamily K member 17
External IDs	OMIM: 607370; HomoloGene: 88928; GeneCards: KCNK17; OMA:KCNK17 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	39,314,461 bp
RNA expression pattern
	Top expressed in
	ascending aorta; ; Descending thoracic aorta; ; right coronary artery; ; islet of Langerhans; ; left coronary artery; ; right lung; ; upper lobe of lung; ; upper lobe of left lung; ; lower lobe of lung; ; tibia;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated ion channel activity; potassium channel activity; potassium ion leak channel activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; ion transport; potassium ion transmembrane transport; stabilization of membrane potential;
	Sources:Amigo / QuickGO
Orthologs
	89822
	n/a
	ENSG00000124780
	n/a
	Q96T54
	n/a
	NM_001135111; NM_031460
	n/a
	NP_001128583; NP_113648
	n/a
	Wikidata
View/Edit Human

Potassium channel subfamily K member 17 is a protein that in humans is encoded by the KCNK17 gene.^[3]^[4]

This gene encodes K_2P17.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel, primarily expressed in the pancreas, is activated at alkaline pH.^[4]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000124780 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106. S2CID 7356601.
^ ^a ^b "Entrez Gene: KCNK17 potassium channel, subfamily K, member 17".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000124780 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16382106-3] Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106. S2CID 7356601.

[entrez-4] "Entrez Gene: KCNK17 potassium channel, subfamily K, member 17".

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