Karen Vousden

Karen Heather Vousden
CBE, FRS, FRSE, FMedSci
Born (1957-07-19) 19 July 1957 (age 67)[4]
Alma materQueen Mary and Westfield College[4]
Known forWork on p53 tumour suppressor protein[5][6] and Mdm2 protein[7]
Spouse
Robert Ludwig
​
(m. 1986)​
[4]
Awards
Scientific career
FieldsCancer[2][3]
Institutions
ThesisUse of suppressor gene mutations to study transfer RNA redundancy in Coprinus (1982)

Karen Heather Vousden (born 19 July 1957)[4] is a British medical researcher. She is known for her work on the tumour suppressor protein, p53, and in particular her discovery of the important regulatory role of Mdm2, an attractive target for anti-cancer agents. From 2003 to 2016, she was the director of the Cancer Research UK Beatson Institute in Glasgow, UK, moving back to London in 2016 to take up the role of Chief Scientist at CRUK and Group Leader at the Francis Crick Institute.

  1. ^ Cite error: The named reference frse was invoked but never defined (see the help page).
  2. ^ Evan, Gerard I.; Vousden, Karen H. (2001). "Proliferation, cell cycle and apoptosis in cancer". Nature. 411 (6835): 342–348. Bibcode:2001Natur.411..342E. doi:10.1038/35077213. PMID 11357141. S2CID 4414024.
  3. ^ Peters G, Vousden KH, eds. Oncogenes and Tumour Suppressors (Oxford University Press; 1997) (ISBN 0199635951)
  4. ^ a b c d e "Vousden, Prof. Karen Heather, (Mrs R. Ludwig)". Who's Who. Vol. 2016 (online Oxford University Press ed.). Oxford: A & C Black. (Subscription or UK public library membership required.)
  5. ^ Sedwick, C. (2012). "Karen Vousden: Getting the big picture on p53". The Journal of Cell Biology. 198 (2): 148–149. doi:10.1083/jcb.1982pi. PMC 3410416. PMID 22826118.
  6. ^ Yee, K. S.; Vousden, K. H. (2005). "Complicating the complexity of p53". Carcinogenesis. 26 (8): 1317–1322. doi:10.1093/carcin/bgi122. PMID 15888490.
  7. ^ Cite error: The named reference mdm2 was invoked but never defined (see the help page).