Kawano (written: 河野, 川野 or かわの in hiragana) is a Japanese surname. Notable people with the surname include:
- Hiroki Kawano (河野 広貴, born 1990), Japanese footballer
- Junji Kawano (川野 淳次, born 1945), Japanese footballer
- Junko Kawano (河野 純子), Japanese game designer, game director and writer
- Kaoru Kawano, (born 1916), Japanese artist, known for wood blocks
- Katsumi Kawano (河野 かつみ, born 1965), Japanese volleyball player
- Kazumasa Kawano (河野 和正, born 1970), Japanese footballer
- Katsutoshi Kawano (河野 克俊, born 1954), Japanese admiral
- Keizoh Kawano (河野 啓三), keyboardist for Japanese jazz fusion band T-Square
- Kenichi Kawano (河野 健一), Japanese footballer
- Koichiro Kawano (born 1981), Japanese golfer
- Naoki Kawano (川野 直輝, born 1982), Japanese actor and musician
- Otoya Kawano (かわの をとや), Japanese voice actor
- Shinichi Kawano (河野 真一, born 1969), Japanese footballer
- Takashi Kawano (河野 貴志, born 1996), Japanese footballer
- Yosh Kawano (1921-2018), Chicago Cubs clubhouse manager