Keese Mill—better known locally as Keese's Mills, but also spelled as Keeses Mill and Keeses Mills—is a hamlet west of Paul Smiths in the Town of Brighton, Franklin County, New York, United States, in the Adirondacks. It is named for a settlement established by employees of the two sawmills established by Keese and Tomlinson near their dam on the outlet of Lower St. Regis Lake Saint Regis River in mid-nineteenth century.
Keese Mill road, which starts at Paul Smiths, is the only road in the hamlet; it provides access to Black Pond and Long Pond, trails to Saint Regis and Jenkins Mountains and the Saint Regis Esker Trail, and the middle branch of the Saint Regis River. At present, before reaching its end, it transitions to an unpaved dirt road, and at its end, it becomes the Blue Mountain Road and continues onward to NYS Route 458. The middle section is a seasonal road closed to traffic during the winter season.