| Kelch motif | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Structure of Galactose oxidase containing kelch repeats.[1] | |||||||||
| Identifiers | |||||||||
| Symbol | Kelch_1 | ||||||||
| Pfam | PF01344 | ||||||||
| InterPro | IPR006652 | ||||||||
| SMART | Kelch | ||||||||
| SCOP2 | 1gof / SCOPe / SUPFAM | ||||||||
| OPM superfamily | 319 | ||||||||
| OPM protein | 3ii7 | ||||||||
| |||||||||
| Kelch motif | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Kelch_2 | ||||||||
| Pfam | PF07646 | ||||||||
| Pfam clan | CL0186 | ||||||||
| InterPro | IPR011498 | ||||||||
| SCOP2 | 1gof / SCOPe / SUPFAM | ||||||||
| |||||||||
| Galactose oxidase, central domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Kelch_3 | ||||||||
| Pfam | PF13415 | ||||||||
| Pfam clan | CL0186 | ||||||||
| |||||||||
| Galactose oxidase, central domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Kelch_4 | ||||||||
| Pfam | PF13418 | ||||||||
| Pfam clan | CL0186 | ||||||||
| |||||||||
| Kelch motif | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Kelch_5 | ||||||||
| Pfam | PF13854 | ||||||||
| Pfam clan | CL0186 | ||||||||
| |||||||||
| Kelch motif | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Kelch_6 | ||||||||
| Pfam | PF13964 | ||||||||
| Pfam clan | CL0186 | ||||||||
| |||||||||
The Kelch motif is a region of protein sequence found widely in proteins from bacteria and eukaryotes.[2] This sequence motif is composed of about 50 amino acid residues which form a structure of a four stranded beta-sheet "blade". This sequence motif is found in between five and eight tandem copies per protein which fold together to form a larger circular solenoid structure called a beta-propeller domain.
- ^ Ito N, Phillips SE, Stevens C, et al. (March 1991). "Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase". Nature. 350 (6313): 87–90. doi:10.1038/350087a0. PMID 2002850. S2CID 4345713.
- ^ Adams J, Kelso R, Cooley L (January 2000). "The kelch repeat superfamily of proteins: propellers of cell function". Trends Cell Biol. 10 (1): 17–24. doi:10.1016/S0962-8924(99)01673-6. PMID 10603472.