Kelch protein

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Kelch motif
Identifiers
Symbol	Kelch_1
Pfam	PF01344
InterPro	IPR006652
SCOP2	1gof / SCOPe / SUPFAM
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary PDB 1u6dX:459–504 1zgkA:459–504 1goh :311–357 1gof :311–357 1gog :311–357

Kelch proteins (and Kelch-like proteins) are a widespread group of proteins that contain multiple Kelch motifs. The kelch domain generally occurs as a set of five to seven kelch tandem repeats that form a β-propeller tertiary structure. Kelch-repeat β-propellers are generally involved in protein–protein interactions, though the large diversity of domain architectures and limited sequence identity between kelch motifs make characterisation of the kelch superfamily difficult.