 Kentucky Route 21 | ||||
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| Route information | ||||
| Maintained by KYTC | ||||
| Length | 17.284 mi[1] (27.816 km) | |||
| Major junctions | ||||
| West end |  KY 52 near Paint Lick | |||
 I-75 in Berea US 25 in Berea US 421 in Bighill | ||||
| East end | Jackson County line | |||
| Location | ||||
| Country | United States | |||
| State | Kentucky | |||
| Counties | Madison | |||
| Highway system | ||||
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Kentucky Route 21 (KY 21) is a 14.196-mile (22.846 km) west–east highway in Madison County, running from the Garrard County line near Paint Lick to Bighill, east of Berea.
It begins at KY 52 at the Garrard County line at the Paint Lick Creek Bridge. The road passes through Wallaceton and traverses over Interstate 75 in Berea, where KY 21 shortly runs along with US 25. After US 25 breaks away and goes north toward the Blue Grass Army Depot, KY 21 continues to the east and intersects US 421 in Bighill before ending at the Jackson County line.