Keratin 10

KRT10
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4F1Z, 3ASW, 4ZRY
Identifiers
Aliases	KRT10, BCIE, BIE, CK10, EHK, K10, KPP, keratin 10
External IDs	OMIM: 148080; MGI: 96685; GeneCards: KRT10; OMA:KRT10 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	40,822,614 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	99,280,190 bp
RNA expression pattern
	Top expressed in
	skin of thigh; ; skin of arm; ; vulva; ; nipple; ; human penis; ; skin of hip; ; skin of abdomen; ; gums; ; gingival epithelium; ; sperm;
	Top expressed in
	skin of external ear; ; lip; ; condyle; ; skin of abdomen; ; belly cord; ; skin of back; ; human fetus; ; fossa; ; saccule; ; otic placode;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	structural molecule activity; structural constituent of skin epidermis; protein heterodimerization activity; protein binding;
Cellular component	cytoplasm; extracellular exosome; intermediate filament; membrane; nucleus; extracellular space; cytosol; cornified envelope; extracellular region; cell surface;
Biological process	keratinocyte differentiation; keratinization; cornification; peptide cross-linking; positive regulation of epidermis development; protein heterotetramerization;
	Sources:Amigo / QuickGO
Orthologs
	3858
	16661
	ENSG00000186395
	ENSMUSG00000019761
	P13645
	P02535
	NM_000421; NM_001379366
	NM_010660
	NP_000412; NP_001366295
	NP_034790
	Wikidata
View/Edit Human	View/Edit Mouse

Keratin, type I cytoskeletal 10 also known as cytokeratin-10 (CK-10) or keratin-10 (K10) is a protein that in humans is encoded by the KRT10 gene.^[5]^[6]^[7] Keratin 10 is a type I keratin.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186395 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000019761 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lessin SR, Huebner K, Isobe M, Croce CM, Steinert PM (Jan 1989). "Chromosomal mapping of human keratin genes: evidence of non-linkage". J Invest Dermatol. 91 (6): 572–8. doi:10.1111/1523-1747.ep12477087. PMID 2461420.
^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
^ "Entrez Gene: KRT10 keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000186395 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000019761 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2461420-5] Lessin SR, Huebner K, Isobe M, Croce CM, Steinert PM (Jan 1989). "Chromosomal mapping of human keratin genes: evidence of non-linkage". J Invest Dermatol. 91 (6): 572–8. doi:10.1111/1523-1747.ep12477087. PMID 2461420.

[pmid16831889-6] Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.

[entrez-7] "Entrez Gene: KRT10 keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris)".

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