Keratin 19

KRT19
Identifiers
Aliases	KRT19, CK19, K19, K1CS, keratin 19
External IDs	OMIM: 148020; MGI: 96693; HomoloGene: 1713; GeneCards: KRT19; OMA:KRT19 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	41,528,308 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	100,039,491 bp
RNA expression pattern
	Top expressed in
	palpebral conjunctiva; ; mucosa of transverse colon; ; nasal epithelium; ; mucosa of sigmoid colon; ; olfactory zone of nasal mucosa; ; amniotic fluid; ; epithelium of nasopharynx; ; epithelium of bronchus; ; gallbladder; ; bronchial epithelial cell;
	Top expressed in
	epithelium of stomach; ; crypt of lieberkuhn of small intestine; ; mucous cell of stomach; ; transitional epithelium of urinary bladder; ; pyloric antrum; ; left colon; ; duodenum; ; conjunctival fornix; ; ileum; ; lactiferous gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein-containing complex binding; structural constituent of muscle; structural constituent of cytoskeleton; protein binding; structural molecule activity;
Cellular component	terminal web; plasma membrane; sarcolemma; costamere; dystrophin-associated glycoprotein complex; Z discdkac; extracellular exosome; intermediate filament; cell periphery; cytosol; apicolateral plasma membrane;
Biological process	Notch signaling pathway; viral process; sarcomere organization; cell differentiation involved in embryonic placenta development; response to estrogen; keratinization; cornification;
	Sources:Amigo / QuickGO
Orthologs
	3880
	16669
	ENSG00000171345
	ENSMUSG00000020911
	P08727
	P19001
	NM_002276
	NM_008471; NM_001313963
	NP_002267
	NP_001300892; NP_032497
	Wikidata
View/Edit Human	View/Edit Mouse

Keratin, type I cytoskeletal 19 (Keratin-19)) also known as cytokeratin-19 (CK-19) is a 40 kDa protein that in humans is encoded by the KRT19 gene.^[5]^[6] Keratin-19 is a type I keratin.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171345 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020911 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". The Journal of Cell Biology. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
^ "Entrez Gene: KRT19 keratin 19".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000171345 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020911 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16831889-5] Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". The Journal of Cell Biology. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.

[entrez-6] "Entrez Gene: KRT19 keratin 19".

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