Ketan J. Patel

Ketan J. Patel
FRS FMedSci MRCP
Patel in 2015
Born
Ketan Jayakrishna Patel

Nairobi, Kenya[5]
Nationality
EducationBanda School
Marlborough College
Alma mater
AwardsEMBO Member
Scientific career
Fields
Institutions
ThesisAntigen presentation by the B cell antigen receptor (1994)
Doctoral advisorMichael Neuberger[3][4]
Website

www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/kj-patel/

Ketan Jayakrishna Patel[5] is a British–Kenyan scientist who is Director of the MRC Weatherall Institute of Molecular Medicine and the MRC Molecular Haematology Unit at the University of Oxford.[7] Until 2020 he was a tenured principal investigator at the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB).[8][9][10][11][12]

  1. ^ Joenje, H; Patel, K. J. (2001). "The emerging genetic and molecular basis of Fanconi anaemia". Nature Reviews Genetics. 2 (6): 446–57. doi:10.1038/35076590. PMID 11389461. S2CID 14130453.
  2. ^ Niedzwiedz, W; Mosedale, G; Johnson, M; Ong, C. Y.; Pace, P; Patel, K. J. (2004). "The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair". Molecular Cell. 15 (4): 607–20. doi:10.1016/j.molcel.2004.08.009. PMID 15327776.
  3. ^ Patel, K.J.; Neuberger, M.S. (1993). "Antigen presentation by the B cell antigen receptor is driven by the αβ sheath and occurs independently of its cytoplasmic tyrosines". Cell. 74 (5): 939–946. doi:10.1016/0092-8674(93)90473-4. ISSN 0092-8674. PMID 8374958. S2CID 140208777.
  4. ^ Ketan J. Patel (1 December 2013). "Michael Neuberger obituary: Biochemist who discovered how antibodies are greatly improved". The Guardian. Archived from the original on 27 March 2015.
  5. ^ a b "PATEL, Dr Ketan Jayakrishna". Who's Who. Vol. 2016 (online Oxford University Press ed.). Oxford: A & C Black. (Subscription or UK public library membership required.)
  6. ^ "Ketan J. Patel CV". University of Cambridge. Archived from the original on 21 July 2013.
  7. ^ "MRC Molecular Haematology Unit appoints new Director". Medical Research Council. 1 April 2020. Archived from the original on 23 September 2020. Retrieved 14 November 2020.
  8. ^ Pace, P; Mosedale, G; Hodskinson, M. R.; Rosado, I. V.; Sivasubramaniam, M; Patel, K. J. (2010). "Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway". Science. 329 (5988): 219–23. Bibcode:2010Sci...329..219P. doi:10.1126/science.1192277. PMID 20538911. S2CID 206527645.
  9. ^ Crossan, G. P.; Van Der Weyden, L; Rosado, I. V.; Langevin, F; Gaillard, P. H.; McIntyre, R. E.; Sanger Mouse Genetics, Project; Gallagher, F; Kettunen, M. I.; Lewis, D. Y.; Brindle, K; Arends, M. J.; Adams, D. J.; Patel, K. J. (2011). "Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia". Nature Genetics. 43 (2): 147–52. doi:10.1038/ng.752. PMC 3624090. PMID 21240276. Open access icon
  10. ^ Joenje, H (2011). "Metabolism: Alcohol, DNA and disease". Nature. 475 (7354): 45–6. doi:10.1038/475045a. PMID 21734701.
  11. ^ Patel, K. J.; Yu, V. P.; Lee, H; Corcoran, A; Thistlethwaite, F. C.; Evans, M. J.; Colledge, W. H.; Friedman, L. S.; Ponder, B. A.; Venkitaraman, A. R. (1998). "Involvement of Brca2 in DNA repair". Molecular Cell. 1 (3): 347–57. doi:10.1016/s1097-2765(00)80035-0. PMID 9660919.
  12. ^ Carpten, J. D.; Faber, A. L.; Horn, C; Donoho, G. P.; Briggs, S. L.; Robbins, C. M.; Hostetter, G; Boguslawski, S; Moses, T. Y.; Savage, S; Uhlik, M; Lin, A; Du, J; Qian, Y. W.; Zeckner, D. J.; Tucker-Kellogg, G; Touchman, J; Patel, K; Mousses, S; Bittner, M; Schevitz, R; Lai, M. H.; Blanchard, K. L.; Thomas, J. E. (2007). "A transforming mutation in the pleckstrin homology domain of AKT1 in cancer". Nature. 448 (7152): 439–44. Bibcode:2007Natur.448..439C. doi:10.1038/nature05933. PMID 17611497. S2CID 4302164.