Kethoxal

Kethoxal
Names
IUPAC name
3-Ethoxy-1,1-dihydroxy-2-butanone
Other names
3-Ethoxy-2-oxobutyraldehyde hydrate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.215.334 Edit this at Wikidata
KEGG
MeSH C005135
UNII
  • InChI=1S/C6H12O4/c1-3-10-4(2)5(7)6(8)9/h4,6,8-9H,3H2,1-2H3
    Key: YRCRRHNVYVFNTM-UHFFFAOYSA-N
  • CCOC(C)C(=O)C(O)O
Properties
C6H12O4
Molar mass 148.158 g·mol−1
Appearance Pale yellow syrup[1]
Boiling point 145 °C (293 °F; 418 K)[1][2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Kethoxal (3-ethoxy-1,1-dihydroxy-2-butanone) is an organic compound that has antiviral and anaplasmosis properties.[1][3] It also forms a stable covalent adduct with guanine, which makes it useful for nucleic acid structure determination.[4]

  1. ^ a b c J. Elks (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 510. ISBN 9781475720853.
  2. ^ SciFinder record for CASRN 27762-78-3
  3. ^ "Kethoxal". Merriam-Webster.
  4. ^ Robert Shapiro; Bertram I. Cohen; Shian-Jan Shiuey; Hans Maurer (1969). "Reaction of guanine with glyoxal, pyruvaldehyde, and kethoxal, and the structure of the acylguanines. Synthesis of N2-alkylguanines". Biochemistry. 8 (1): 238–245. doi:10.1021/bi00829a034. PMID 5777326.