Kikuchi disease

Kikuchi disease
Other namesHistiocytic necrotizing lymphadenitis, Kikuchi-Fujimoto disease
Micrograph of a lymph node with Kikuchi disease showing the characteristic features (abundant histiocytes, necrosis without neutrophils). H&E stain.
SpecialtyAngiology Edit this on Wikidata

Kikuchi disease was described in 1972 in Japan. It is also known as histiocytic necrotizing lymphadenitis, Kikuchi necrotizing lymphadenitis, phagocytic necrotizing lymphadenitis, subacute necrotizing lymphadenitis, and necrotizing lymphadenitis.[1][2][3][4] Kikuchi disease occurs sporadically in people with no family history of the condition.[5]

It was first described by Dr Masahiro Kikuchi (1935–2012) in 1972[6] and independently by Y. Fujimoto.

  1. ^ Rammohan A, Cherukuri SD, Manimaran AB, Manohar RR, Naidu RM (June 2012). "Kikuchi-Fujimoto Disease: A Sheep in Wolf's Clothing". J Otolaryngol Head Neck Surg. 41 (3): 222–26. PMID 22762705.
  2. ^ Kaushik V, Malik TH, Bishop PW, Jones PH (June 2004). "Histiocytic necrotising lymphadenitis (Kikuchi's disease): a rare cause of cervical lymphadenopathy". Surgeon. 2 (3): 179–82. doi:10.1016/s1479-666x(04)80084-2. PMID 15570824.
  3. ^ Bosch X, Guilabert A (2006). "Kikuchi-Fujimoto disease". Orphanet J Rare Dis. 1: 18. doi:10.1186/1750-1172-1-18. PMC 1481509. PMID 16722618.
  4. ^ Bosch X, Guilabert A, Miquel R, Campo E (July 2004). "Enigmatic Kikuchi-Fujimoto disease: a comprehensive review". Am. J. Clin. Pathol. 122 (1): 141–52. doi:10.1309/YF08-1L4T-KYWV-YVPQ. PMID 15272543.
  5. ^ "kikuchi disease". Archived from the original on 8 May 2019. Retrieved 17 April 2018.
  6. ^ Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytes. Acta Hematol Jpn 1972;35:379–80.