L3MBTL2

L3MBTL2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2W0T, 3CEY, 3F70
Identifiers
Aliases	L3MBTL2, H-l(3)mbt-l, L3MBT, L3MBTL2 polycomb repressive complex 1 subunit, polycomb repressive complex 1 subunit, L3MBTL histone methyl-lysine binding protein 2
External IDs	OMIM: 611865; MGI: 2443584; HomoloGene: 12882; GeneCards: L3MBTL2; OMA:L3MBTL2 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	41,231,271 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	81,572,516 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; tibialis anterior muscle; ; parotid gland; ; nasal epithelium; ; skin of arm; ; mucosa of ileum; ; cerebellar vermis; ; external globus pallidus; ; gingival epithelium; ; right frontal lobe;
	Top expressed in
	spermatocyte; ; epiblast; ; otolith organ; ; hand; ; utricle; ; cumulus cell; ; superior cervical ganglion; ; tail of embryo; ; primary oocyte; ; seminiferous tubule;
	More reference expression data
	n/a
Gene ontology
Molecular function	histone binding; zinc ion binding; protein binding; metal ion binding; methylated histone binding;
Cellular component	nucleus; nucleoplasm;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of G0 to G1 transition; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	83746
	214669
	ENSG00000100395
	ENSMUSG00000022394
	Q969R5
	P59178
	NM_001003689; NM_031488
	NM_001289711; NM_001289712; NM_145993
	NP_113676
	NP_001276640; NP_001276641; NP_666105
	Wikidata
View/Edit Human	View/Edit Mouse

Lethal(3)malignant brain tumor-like 2 protein is a protein that in humans is encoded by the L3MBTL2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100395 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022394 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wismar J (Oct 2001). "Molecular characterization of h-l(3)mbt-like: a new member of the human mbt family". FEBS Letters. 507 (1): 119–21. doi:10.1016/S0014-5793(01)02959-3. PMID 11682070.
^ "Entrez Gene: L3MBTL2 l(3)mbt-like 2 (Drosophila)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000100395 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022394 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11682070-5] Wismar J (Oct 2001). "Molecular characterization of h-l(3)mbt-like: a new member of the human mbt family". FEBS Letters. 507 (1): 119–21. doi:10.1016/S0014-5793(01)02959-3. PMID 11682070.

[entrez-6] "Entrez Gene: L3MBTL2 l(3)mbt-like 2 (Drosophila)".

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