LEAPER (Leveraging endogenous ADAR for programmable editing of RNA) is a genetic engineering technique in molecular biology by which RNA can be edited. The technique relies on engineered strands of RNA to recruit native ADAR enzymes to swap out different compounds in RNA. Developed by researchers at Peking University in 2019, the technique, some have claimed, is more efficient than the CRISPR gene editing technique.[1] Initial studies have claimed that editing efficiencies of up to 80%.
- ^ Murphy F, Walsh M (July 15, 2019). "Peking University Scientists Pioneer New Gene-Editing Technology". Caixin. Archived from the original on October 28, 2020. Retrieved August 25, 2020.