LGP2

DHX58
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDHX58, D11LGP2, D11lgp2e, LGP2, RLR-3, DEXH-box helicase 58
External IDsOMIM: 608588; MGI: 1931560; HomoloGene: 69371; GeneCards: DHX58; OMA:DHX58 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_024119

NM_030150

RefSeq (protein)

NP_077024

NP_084426

Location (UCSC)Chr 17: 42.1 – 42.11 MbChr 11: 100.59 – 100.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable ATP-dependent RNA helicase DHX58 also known as RIG-I-like receptor 3 (RLR-3) or RIG-I-like receptor LGP2 (RLR) is a RIG-I-like receptor dsRNA helicase enzyme that in humans is encoded by the DHX58 gene.[5][6] The protein encoded by the gene DHX58 is known as LGP2 (Laboratory of Genetics and Physiology 2).[5][7][8]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000108771Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017830Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Cui Y, Li M, Walton KD, Sun K, Hanover JA, Furth PA, Hennighausen L (Dec 2001). "The Stat3/5 locus encodes novel endoplasmic reticulum and helicase-like proteins that are preferentially expressed in normal and neoplastic mammary tissue". Genomics. 78 (3): 129–34. doi:10.1006/geno.2001.6661. hdl:2027.42/175385. PMID 11735219.
  6. ^ "Entrez Gene: LGP2 likely ortholog of mouse D11lgp2".
  7. ^ Cite error: The named reference Childs_2012 was invoked but never defined (see the help page).
  8. ^ Matsumiya T, Stafforini DM (2010). "Function and regulation of retinoic acid-inducible gene-I". Crit. Rev. Immunol. 30 (6): 489–513. doi:10.1615/critrevimmunol.v30.i6.10. PMC 3099591. PMID 21175414.