LRPPRC

LRPPRC
Identifiers
Aliases	LRPPRC, CLONE-23970, GP130, LRP130, LSFC, leucine rich pentatricopeptide repeat containing, MC4DN5
External IDs	OMIM: 607544; MGI: 1919666; HomoloGene: 32695; GeneCards: LRPPRC; OMA:LRPPRC - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	43,996,226 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	85,098,217 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; biceps brachii; ; mucosa of sigmoid colon; ; body of tongue; ; kidney tubule; ; Skeletal muscle tissue of biceps brachii; ; gonad; ; jejunum; ; mucosa of transverse colon; ; skin of thigh;
	Top expressed in
	cardiac muscle tissue of left ventricle; ; interventricular septum; ; choroid plexus of fourth ventricle; ; plantaris muscle; ; extensor digitorum longus muscle; ; epiblast; ; extraocular muscle; ; right ventricle; ; soleus muscle; ; thoracic diaphragm;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; single-stranded DNA binding; microtubule binding; ubiquitin protein ligase binding; beta-tubulin binding; actin filament binding; DNA binding; endonuclease activity; RNA binding;
Cellular component	condensed nuclear chromosome; nuclear inner membrane; mitochondrial nucleoid; perinuclear region of cytoplasm; cytoplasm; cytoskeleton; nucleoplasm; microtubule; nuclear outer membrane; membrane; mitochondrion; nucleus; ribonucleoprotein complex;
Biological process	regulation of transcription, DNA-templated; mRNA transport; mitochondrion transport along microtubule; transcription, DNA-templated; negative regulation of mitochondrial RNA catabolic process; regulation of mitochondrial translation; RNA modification; nucleic acid phosphodiester bond hydrolysis; transport;
	Sources:Amigo / QuickGO
Orthologs
	10128
	72416
	ENSG00000138095
	ENSMUSG00000024120
	P42704
	Q6PB66
	NM_133259
	NM_028233
	NP_573566
	NP_082509
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine-rich PPR motif-containing protein, mitochondrial is a protein that in humans is encoded by the LRPPRC gene.^[5]^[6]^[7] Transcripts ranging in size from 4.8 to 7.0 kb which result from alternative polyadenylation have been reported for this gene.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000138095 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024120 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hou J, Wang F, McKeehan WL (Jul 1994). "Molecular cloning and expression of the gene for a major leucine-rich protein from human hepatoblastoma cells (HepG2)". In Vitro Cell Dev Biol Anim. 30A (2): 111–4. doi:10.1007/BF02631402. PMID 8012652. S2CID 24824618.
^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
^ ^a ^b "Entrez Gene: LRPPRC leucine-rich PPR-motif containing".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000138095 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024120 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8012652-5] Hou J, Wang F, McKeehan WL (Jul 1994). "Molecular cloning and expression of the gene for a major leucine-rich protein from human hepatoblastoma cells (HepG2)". In Vitro Cell Dev Biol Anim. 30A (2): 111–4. doi:10.1007/BF02631402. PMID 8012652. S2CID 24824618.

[pmid8619474-6] Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

[entrez-7] "Entrez Gene: LRPPRC leucine-rich PPR-motif containing".

[1]

[2]

[3]

[4]

[5]

[6]

[7]