LSD-Pip is a compound from the ergoline family, related to LSD but with the N,N-diethyl substitution replaced by a piperidine group. It is more potent than the corresponding pyrrolidine and morpholine analogues (LPD-824 and LSM-775 respectively), but is still several times less potent than LSD as a 5-HT2Aagonist.[1] Early studies suggested this compound to be inactive as a psychedelic in humans,[2] though this does not seem to have been confirmed by any more recent work.
^Braden MR (2007). Towards a biophysical understanding of hallucinogen action (Ph.D. thesis). Purdue University. ProQuest304838368.
^Cerletti A, Doepfner W (January 1958). "Comparative study on the serotonin antagonism of amide derivatives of lysergic acid and of ergot alkaloids". The Journal of Pharmacology and Experimental Therapeutics. 122 (1): 124–36. PMID13502837.