| Lactobacillus crispatus | |
|---|---|
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Bacillota |
| Class: | Bacilli |
| Order: | Lactobacillales |
| Family: | Lactobacillaceae |
| Genus: | Lactobacillus |
| Species: | L. crispatus
|
| Binomial name | |
| Lactobacillus crispatus (Brygoo and Aladame 1953)
Moore and Holdeman 1970 | |
Lactobacillus crispatus is a common, rod-shaped species of genus Lactobacillus and is a lactic acid producing bacterial species located in both the vagina, through vaginal discharge, and the vertebrate gastrointestinal tract.[1] This species commonly found in vaginal microbiome and is thought to be beneficial to health.[2]
Some strains are commercially available as a probiotic that can be used by premenopausal and postmenopausal women that experience recurrent urinary tract infections.[3][4] For example, one strain CTV-05 is being evaluated specifically for the prevention and treatment of bacterial vaginosis,[5] which is characterized by overgrowth of other bacteria, potentially as a result of the absence of Lactobacillus flora that can serve to protect the host from infection.[6]
- ^ Ojala T, Kuparinen V, Koskinen JP, Alatalo E, Holm L, Auvinen P, Edelman S, Westerlund-Wikström B, Korhonen TK, Paulin L, Kankainen M (July 2010). "Genome sequence of Lactobacillus crispatus ST1". Journal of Bacteriology. 192 (13): 3547–8. doi:10.1128/JB.00399-10. PMC 2897677. PMID 20435723.
- ^ Ravel, J; Gajer, P; Abdo, Z; Schneider, GM; Koenig, SS; McCulle, SL; Karlebach, S; Gorle, R; Russell, J; Tacket, CO; Brotman, RM; Davis, CC; Ault, K; Peralta, L; Forney, LJ (15 March 2011). "Vaginal microbiome of reproductive-age women". Proceedings of the National Academy of Sciences of the United States of America. 108 Suppl 1 (Suppl 1): 4680–7. doi:10.1073/pnas.1002611107. PMC 3063603. PMID 20534435.
- ^ Antonio MA, Hillier SL (May 2003). "DNA fingerprinting of Lactobacillus crispatus strain CTV-05 by repetitive element sequence-based PCR analysis in a pilot study of vaginal colonization". Journal of Clinical Microbiology. 41 (5): 1881–7. doi:10.1128/jcm.41.5.1881-1887.2003. PMC 154705. PMID 12734221.
- ^ Dwyer JP, Dwyer PL (August 2013). "Lactobacillus probiotics may prevent recurrent UTIs in postmenopausal women". Evidence Based Medicine. 18 (4): 141–142. doi:10.1136/eb-2012-100961. PMID 23125237. S2CID 41235446.
- ^ Antonio MA, Meyn LA, Murray PJ, Busse B, Hillier SL (May 2009). "Vaginal colonization by probiotic Lactobacillus crispatus CTV-05 is decreased by sexual activity and endogenous Lactobacilli". The Journal of Infectious Diseases. 199 (10): 1506–13. doi:10.1086/598686. PMID 19331578.
- ^ Vásquez A, Jakobsson T, Ahrné S, Forsum U, Molin G (August 2002). "Vaginal lactobacillus flora of healthy Swedish women". Journal of Clinical Microbiology. 40 (8): 2746–9. doi:10.1128/JCM.40.8.2746-2749.2002. PMC 120688. PMID 12149323.