| Charlotte of Hesse-Kassel | |
|---|---|
 Charlotte in 1650, by the Atelier of the Beaubrun Brothers | |
| Electress Palatine | |
| Tenure | 22 February 1650 – 14 April 1657 |
| Born | 20 November 1627 Kassel, Germany |
| Died | 26 March 1686 (aged 58) Heidelberg Castle, Heidelberg, Germany |
| Spouse | |
| Issue | |
| House | Hesse-Kassel |
| Father | William V, Landgrave of Hesse-Kassel |
| Mother | Amalie Elisabeth of Hanau-Münzenberg |
| Religion | Calvinism |
Charlotte of Hesse-Kassel (20 November 1627 – 26 March 1686), was a German princess of the House of Hesse-Kassel and by marriage Electress Palatine during 1650–1657 as the first wife of Charles I Louis, although the validity of the divorce was disputed. Through her daughter Elisabeth Charlotte, Duchess of Orléans, she was the direct ancestress of House of Orléans and the Houses of Habsburg-Lorraine and Habsburg-Este.