Large neutral amino acids transporter small subunit 1

SLC7A5
Identifiers
Aliases	SLC7A5, 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1, solute carrier family 7 member 5
External IDs	OMIM: 600182; MGI: 1298205; HomoloGene: 55759; GeneCards: SLC7A5; OMA:SLC7A5 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	87,869,507 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	122,634,433 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; beta cell; ; dorsal motor nucleus of vagus nerve; ; mucosa of pharynx; ; inferior olivary nucleus; ; mucosa of esophagus; ; body of tongue; ; corpus epididymis; ; left testis; ; right testis;
	Top expressed in
	lacrimal gland; ; fetal liver hematopoietic progenitor cell; ; lens; ; seminal vesicula; ; spermatocyte; ; calvaria; ; optic nerve; ; parotid gland; ; seminiferous tubule; ; blood;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptide antigen binding; L-amino acid transmembrane transporter activity; amino acid transmembrane transporter activity; neutral amino acid transmembrane transporter activity; antiporter activity; protein binding; transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; intracellular membrane-bounded organelle; plasma membrane; apical plasma membrane; extracellular exosome; integral component of plasma membrane; cytoplasm; cytosol;
Biological process	amino acid transmembrane transport; cell differentiation; cellular amino acid metabolic process; nervous system development; multicellular organism development; L-amino acid transport; neutral amino acid transport; leukocyte migration; amino acid transport; L-alpha-amino acid transmembrane transport; transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	8140
	20539
	ENSG00000103257
	ENSMUSG00000040010
	Q01650
	Q9Z127
	NM_003486
	NM_011404
	NP_003477
	NP_035534
	Wikidata
View/Edit Human	View/Edit Mouse

Large neutral amino acids transporter small subunit 1, also known as 4F2 light chain, or CD98 light chain is a protein that in humans is encoded by the SLC7A5 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000103257 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040010 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: solute carrier family 7 (cationic amino acid transporter".
^ "UniProt". www.uniprot.org.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000103257 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000040010 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: solute carrier family 7 (cationic amino acid transporter".

[UniProt-6] "UniProt". www.uniprot.org.

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