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Trade names | Lazcluze, Leclaza |
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Routes of administration | By mouth |
Drug class | EGFR inhibitor |
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Formula | C30H34N8O3 |
Molar mass | 554.655 g·mol−1 |
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Lazertinib, sold under the brand name Lazcluze and Leclaza, is an anti-cancer medication used for the treatment of non-small cell lung cancer.[1][2][3] It is a kinase inhibitor of epidermal growth factor receptor.[1]
The most common adverse reactions include rash, nail toxicity, infusion-related reactions (amivantamab), musculoskeletal pain, edema, stomatitis, venous thromboembolism, paresthesia, fatigue, diarrhea, constipation, COVID-19 infection, hemorrhage, dry skin, decreased appetite, pruritus, nausea, and ocular toxicity.[2]
Lazertinib was approved for medical use in South Korea in January 2021,[4][5] and in the United States in August 2024.[2][6]